Deficiency of natural anticoagulants.
نویسندگان
چکیده
منابع مشابه
An Overview of Novel Anticoagulants
Arterial and venous thromboembolism is one of the most common causes of death worldwide. For almost seventy years, heparin, low molecular weight heparin, and vitamin K antagonists have been widely used in the prevention and treatment of thromboembolic disorders. However, many of the limitations of these traditional anticoagulants have led to the search for and attempts to introduce better drug ...
متن کاملThe risk of recurrent venous thromboembolism in patients with inherited deficiency of natural anticoagulants antithrombin, protein C and protein S.
Few data are available on the risk of recurrent venous thromboembolism (VTE) associated with the rare inherited deficiencies of natural anticoagulants. We studied 602 patients with previous VTE: the incidence of first recurrence in the absence of anticoagulation was retrospectively estimated in 64 patients with deficiency of antithrombin (AT, n=14), protein C (PC, n=28), or protein S (PS, n=22)...
متن کاملVTE recurrence in patients with inherited deficiencies of natural anticoagulants.
Thromb Haemost 2009; 101: 5–6 Venous thromboembolism (VTE) is a serious clinical condition manifesting as deep venous thrombosis (DVT) and/or pulmonary embolism (PE). Patients with VTE have a considerable risk of recurrent VTE that persists for many years (1, 2). In a population based cohort study, Heit et al. (1) found an overall cumulative percentage of VTE recurrence at 180 days, 1 and 10 ye...
متن کاملProtein S deficiency and novel oral anticoagulants: an intriguing case.
Vitamin K dependent protein S (ProS) is a plasma glycoprotein with anticoagulant properties [1]. Its anticoagulant function is well established in the literature based on clinical data, its genetics and on laboratory assays. ProS is able to prolong the clotting time acting as a cofactor for activated protein C. Furthermore, since the 1980’ies it is known that hereditary ProS deficiency (PSD) in...
متن کاملDeficiencies of natural anticoagulants, protein C, protein S, and antithrombin.
Y ou or a family member may have developed a blood clot in one of the deep veins in the body (ie, a deep vein thrombosis, or DVT) or had a blood clot that traveled to the lungs (ie, a pulmonary embolism, or PE). As part of your medical care, your doctor may have evaluated you for conditions that may have contributed to developing a blood clot. Thrombophilia is a condition in which there is an i...
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ژورنال
عنوان ژورنال: SEIBUTSU BUTSURI KAGAKU
سال: 1994
ISSN: 0031-9082,1349-9785
DOI: 10.2198/sbk.38.397